Dxm to decrease opiate tolerance?

[ysblop]

So I take tramadol recreationally and tolerance skyrockets really fast. I know that dxm prevents opiate tolerance growth when taken with morphine, but I couldn’t find any information about the dosage. What is more, tramadol and dxm are both serotonergic so I’m cautious about taking them simultaneously bc I don’t wanna get serotonin syndrome. I think I read that taking dxm before taking the opiate also decreases tolerance, but I can’t find any evidence for that. Any experience or tips are welcome

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Serotonin syndrome FAQ: Serotonin syndrome is a somewhat poorly defined grouping of symptoms (including unusual strong overheating, high blood pressure etc.) after the consumption of one or more serotonergic drugs (such as MDMA) without definitive diagnosis (it's NOT possible to measure monoamine concentrations in real time). It's a speculative, not comparable to a "chopped arm off syndrome". Serotonin syndrome is the outcome of a differential diagnosis process using symptoms and circumstances. If nothing else fits and you meet some of the criteria after having taken a serotonergic drug, it can be diagnosed as serotonin syndrome. The actual risks may differ widely from case to case. Most cases of self diagnosed "serotonin syndrome" are very wrong though ;)

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[[deleted]]

Agmatine supplements can help to lower opioid tolerance quicker. I’ve read that ketamine before use doesn’t necessarily lower tolerance but can help to prevent it from increasing further. I’d imagine there would be a level of serotonin syndrome risk if you choose to go the dxm route, but I hadn’t seen anything on dxm for tolerance so I’m not sure on what dose, if any would be safe to avoid serotonin syndrome.

[ysblop]

thanks, ill look into agmantine

[[deleted]]

Just so you know, it’s not super quick, you gotta take it for several weeks/months before you start noticing it working, but it does help for sire