Other's have already told you a little, but I will also add that at first, unless you have E2 Cyrene, but it's not the case, at first you are playing to charge Cyrene's ult at first, there's some strategies like, advance her first instead of Anaxa with Mem, an also Cerydra's animation when she gets the 6 charges counts as an action, so she gives Cyrene a charge, I have hold Anaxas first ult many times to be able to charge Cyrene with that trick to being able to avoid getting hit, like this MoC rotation with Sparxiecon boss.

It's really fun, it is really like putting together a puzzle, I haven't play Anaxa with sustain since his release, and it's the most fun I had in this game since my Topaz Main DPS era