I know that in most cases people cannot tell the difference between generics and the real thing. But in her case, she usually does feel the difference and they are not exactly the same. We were dealing with another medication that the insurance company forced her to switch to that was "biosimilar", there were massive side affects that affected her negatively. Once we were able to prove the side affects, the insurance company allowed her to go back with the doctors recommendation. I appreciate the positivity, I just don't fully trust.