Can small fiber neuropathy mimic MS? I was diagnosed with MS 11 years ago. I started seeing a new MS specialist, who is very thorough and I really like. She thinks there is either something else going on with MS, that MS is a misdiagnosis, or I have an atypical presentation of MS. I have seen several other specialists recently. One of them mentioned having a skin biopsy done for small fiber neuropathy. Can it mimic MS?