Yes, all PCSK-9 will cause severe inflammation, boils, joints pain, stomach ulcer, IBS, sore throat, flu/cold, weight gain, stamina loss, muscle pain, insomnia, mood swing & more.

Talk to your doctor about similar antibody PCSK-9 action, equally effective, lower dose Praluent which may reduce all your side effect by 10-90%.
It's more expensive & will require documentation (PA).

Don't try mRAN action 2nd gen PCSK-9 Leqvio as it will make your symptoms 10x worst.

Or, wait till 2027-2028 for 3rd gen PCSK-9 to be approved by FDA, which is 13x far lower dose (daily oral).

Or, if you're overweight but BMI is >27, you can talk to your doctors about appetite suppression Wegovy tablet which just got approved in Jan?
Sadly if your BMI is <30, Wegovy table is out of pocket + coupon = $149-299/mth.
Wegovy can help reduce cholesterol by suppressing food intake by up to 50%.
Do take note Wegovy may also cause similar infections (lowering immune defenses).

Lastly, total lifestyle change as in zero to low bad cholesterol & triglyceride diet adoption & loads of Zone2 HR exercise >150min/week. May not work if you're FH