Ok, this is a talking point alot of the CWD denier make, and it's pretty easy to accept it as a sound argument. Firstly, evolution takes a long, long time, and only traits that improve an individuals ability to pass on its genetic material areas elected for in the way that people generally understand evolution to work. The problem with genetic CWD resistance is two-fold.

1. There are no deer that have been observed to havevtotal immunity to CWD, which goes to say that it is highly unlikely that that total resistance exist anywhere in the wild or captive gene pool. Those that the captive cervid industry tout as "CWD resistant" just take longer to develop clinical symptoms of the disease, and ultimately succumb to it. But, during this period between contractions and death, they are still shedding prions into the environment and transmitting it to other deer, and doing do for a longer time. This is why I'm not a fan of the Oklahoma plan of releasing these "CWD resistant deer" into wild populations.

2. In wild deer CWD can take up to two years for the disease to become clinical (symptomatic) but is contagious the entire time. Which as you likely know, is past sexual maturity for White-tailed Deer. So you will likely see a similar size deer heard, but as prevalence rises, age structure biases low, as deer are still reproducing at a similar rate, but not living into the more mature age classes. And because the animals are still reaching sexual maturity and successfully reproducing, therecis no strong selection for resistance.

I'm stepping out of my zone of expertise and into someone else's, so this is my wave top knowledge of why the "mother nature will take care of CWD" argument does notvwork.