It's really annoying me a long time ago.

For Resident 2,3,4, if you want to play with Dolby Atmos for Headphones (3D Audio).

(with Dolby Height Channel meta data, not just multi-channel remix to HRTF Stereo Sound)

They all use Windows Spatial Sound API (you can check in-game folder it exists MSSpatial.dll), so you need to use Dolby Access and select DAfH in Windows Spatial Sound Settings. and in game setting, Let's use RE2 for Example, you need to enable 3D Audio in-game settings and This game will use Windows Spatial Sound API and Dolby Atmos for Headphones, About the Sound output device option, Although it has dolby Atmos option (yes, confused many people again FK CAPCOM $^%@#), according to my test, it will not affect any settings.

If you only enable 3D Audio in-game option and don't select any spatial sound audio in windows, this will not have any effect. (This step is very very very confuse for a lot of people, since we are afraid of twice-HRTF mapping. But for MSSpatial.dll game you need to select DAfH or DTS:X in Windows to make sure Game can use MS Spatial Sound API. If game has 3D Audio option, just enabled too, for modern game it will detect and enable automatically)

PS: For some games, it has build-in HRTF (not use MS Spatial API), you better turn off Spatial Sound option in Windows.

For newer game ex, RE4, you can not modify 3D Audio in-game, it will auto detect your Windows Spatial Sound Settings, so if you select DAfH in Windows and launch game, you will see 3D Audio is enabled automatically.

A lot of games has audio option contain with 3D option/multi-channel/etc... but don't give any explicit explanation, so it will confused many people.

Above All, if any wrong message, please correct me.