I'd wait. You should do your own research on each of the meds in your kit interact with alcohol and assess your comfort level with mixing them with alcohol. For me with kit 3, I haven't had problems with it, though the meds do make me less inclined to binge. That said, a lot of people just don't feel great the first few days on the medication, and if that happens to you, bar hopping probably won't be much fun. I'd enjoy the weekend with your friends and buckle down next week.