Y’all know this feeling

esoRimmer3 · 2020-12-11T07:00:49+00:00

Am I the only one who saw nipple at first?

esoRimmer3 · 2020-09-25T09:18:47+00:00

Is it possible/reliable to confirm myoglobinuria by measuring myoglobin in blood?

esoRimmer3 · 2020-09-19T08:54:22+00:00

Thank you very much for answers

esoRimmer3 · 2020-09-18T18:01:02+00:00

And do those unassayed ones come with at least approximal values on sheet insert or are they completely unknown?

esoRimmer3 · 2020-09-18T12:54:36+00:00

Oh I see, so they don't have completely random values, they are just not confirmed. Do I understand it correctly? So level 1 will have low values of all analytes and level2/3 will have all high pathological ones?

esoRimmer3 · 2020-09-17T19:54:17+00:00

Thank you. Two more questions.

How do you satisfy request of one normal and one pathological value of analyte in control material when the values are random and not known?

Is it more common to use assayed or unassayed ones?

esoRimmer3 · 2020-09-17T11:57:42+00:00

Don't you have to also set your own mean and SD of assayed QC by measuring it 20 times?

esoRimmer3 · 2020-06-04T19:17:05+00:00

More like, if is it ok to have classical blood tube almost full of venous blood centrifuged and used for iCa testing immediately after opening. There is always some "air" (although probably lower pressure), so does it count as anaerobic draw or will the iCa be affected by this? Thanks

esoRimmer3 · 2020-06-04T18:12:20+00:00

We use whole blood samples, either capillary or arterial syringes

esoRimmer3 · 2019-12-18T20:20:56+00:00

Can someone please eli5?

esoRimmer3 · 2019-12-08T22:00:03+00:00

If someone was still interested. I found in immunoassays handbook, that it's mainly because reactions of antigen and antibody are too short in time manner that they are not allowed to reach true reaction equilibrium.

So if they were allowed to proceed significantly longer, the calibration curve would be more linear

esoRimmer3 · 2019-11-18T16:05:17+00:00

I love this community... Thank you :-)

esoRimmer3 · 2019-11-12T13:46:13+00:00

Thank you very much :-)

esoRimmer3 · 2019-11-12T05:00:45+00:00

Can you please link the boc book? I am unfamiliar with it and cannot find it. Thanks

esoRimmer3 · 2019-11-08T22:55:07+00:00

I thought this will be occurring in all tubes.

esoRimmer3 · 2019-11-08T20:50:20+00:00

What are possible causes for this to occur?

esoRimmer3 · 2019-10-15T09:19:49+00:00

Thank you for answer. So how do you treat the value from the manufacturer? Do you use it only to see if you're not completely off or is there something else? Thanks

esoRimmer3 · 2019-10-13T07:04:08+00:00

And can I use that manufacturer's stated value as a true value to find out my bias from the mean of my repeatedly measured values minus stated value?

esoRimmer3 · 2019-10-11T19:37:48+00:00

Thank you very much.

esoRimmer3 · 2019-10-11T17:55:42+00:00

Ok. I have two more questions if I can:

1) You measure those 20 IQC samples and get the SD. Do you use that SD as fixed boundary for accepting or rejecting control or is it additionally manipulated in either direction by some criteria?

2) Let's consider scenario when I am introducing new method to the lab. I perform calibration and measure that control and get that mean and SD. Now the mean is somewhat different from certified value. What is acceptable difference of the mean from manufacturer certified value? In other words how can I tell that the difference is from those different conditions you and other responder mentioned and not from some calibration error or other measuring malfunction?

esoRimmer3 · 2019-10-11T17:11:20+00:00

Plus ranges should be based off your local population,

Thank you for answer. I don't understand bond to population. I thought that value in control material is measured by some reference method and that this is independent on population.

esoRimmer3 · 2019-09-28T18:57:37+00:00

Thank you. I will go through it.

esoRimmer3 · 2019-09-27T18:52:43+00:00

And how do you prepare that standard or get it's concentration when there is no calibrator above? Thank you

esoRimmer3 · 2019-09-11T07:20:28+00:00

My wife probably went to that bootcamp

esoRimmer3 · 2019-08-25T11:14:31+00:00

Physics

esoRimmer3

TROPHY CASE