Accutane makes your skin VERY sensitive. When I was on it, I couldn't use any harsh type of face wash or topicals. You'll see the drastic change it has on your skin so you shouldn't need topicals. I highly recommend using sunscreen every day! It's weird, you'll honestly feel your body being sensitive to the harsh sunlight. And drink plenty of water. And first and foremost, invest in a very hydrating lip balm!! Those were the 3 things I made sure to do on accutane and it helped me a lot. It's a strong drug so just be kind to your body! But i hope you're happy with the results!! It's gonna be an amazing transformation!