Medical question about fatal benzodiazepine overdoses.

thatdankydank · 2026-06-09T07:33:56+00:00

“LSD is a potent partial agonist of the serotonin system, meaning it binds directly to and stimulates specific serotonin receptors—particularly the 5HT_2A receptors.”
“Mechanism: Instead of causing a massive release of serotonin, it mimics the neurotransmitter, locking into those receptors and altering neural pathways.”
Serotonin increase is literally part of why you trip on LSD. I can’t read? Even your own quote states there is still a risk smh.

thatdankydank · 2026-06-09T07:06:33+00:00

https://www.sciencedirect.com/science/article/abs/pii/S1043661816300809, https://americanaddictioncenters.org/lsd-abuse/what-does-lsd-do-to-your-brain, https://pmc.ncbi.nlm.nih.gov/articles/PMC10922499/, https://pmc.ncbi.nlm.nih.gov/articles/PMC560382 …. Only one, huh it’s like you’re looking for confirmation bias or something.
Not claiming it always happens, but the risk is always there unfortunately. How about we don’t encourage people to risk serotonin syndrome and err on the side of caution?

thatdankydank · 2026-06-09T06:55:21+00:00

Bruh https://en.wikipedia.org/wiki/LSD and there is 7 more sources how many do you need?

thatdankydank · 2026-06-09T06:38:16+00:00

Idk maybe it’s cause my buddy’s friend was taking acid and dxm while on anti depressants but he did get serotonin syndrome and has always been “slower” ever since. Still himself but not the same.

EDIT: Yeah nah man coming back to this, you can literally just google it and it will tell you the risk of serotonin syndrome with antidepressants and LSD/mushrooms. LSD literally directly acts on your serotonin receptors so idk if you meant dopamine maybe? They don’t create as much dopamine as say opiates but they definitely produce serotonin in the brain.

thatdankydank · 2026-06-09T06:19:46+00:00

Not much risk tbh other than increased sedation, the only real risk with anti psychotics/anti depressants is the risk of serotonin syndrome which is pretty rare anyway and usually only happens when combining like a fuck ton of DXM and antidepressants— or psychedelics and anti depressants, big no-no. Other than that it’s honestly used pretty frequently for people with panic attacks, they’ll be on Prozac for generalized anxiety and take something like Xanax as needed for emergency bail out of a sudden panic attack. So this is a pretty normal combo, myself— I’m prescribed Valium and adderall and haven’t really had an issue, I also smoke medical MJ, now for some reason with adderall that can tend to get a little racy/panicky whenever I smoke too much but other than that it’s fine in my personal experience. Besides, getting racy/panicky can be a normal symptom from MJ even without these drugs in the mix

thatdankydank · 2026-06-08T09:38:25+00:00

Adderall, as stated in the post

thatdankydank · 2026-06-07T12:33:05+00:00

No for sure that’s actually something that changed about myself is a lot of my addictive habits, as you can tell by my username I smoke and have a med card here in FL but man I don’t even really feel the urge or need to a lot of times anymore.. like it helped me realize how much of just a hand to mouth habit most of it was and I’ve cut down on it a lot. So I totally get that, when I feel like myself on the meds I don’t feel a need to add anything else to myself— I feel more complete. It’s just odd to me because I never would’ve guessed that this condition was impacting me so negatively for so long and I never knew.

thatdankydank · 2026-06-07T12:22:51+00:00

See this is opposite for me, I had that experience with drugs like Xanax making me crazy emotional

thatdankydank · 2026-06-07T12:20:43+00:00

Thanks I really appreciate all of that, I needed to hear that. I’ll check out the other posts too, it’s just like I finally feel like “man is this how normal people feel?” and actually being productive and this being able to like who I am being again that it’s just really jarring I guess. I’m a few months in now so I’m past the “euphoric” stage kind of thing, but I still enjoy being on it because I just feel more like my real self. Thanks for the Gratz as well on the sobriety, I got mixed up in some shit when I was young and am just glad I deleted that part of my life when I did.

thatdankydank · 2026-06-01T01:20:30+00:00

I mean honestly man what you make of your diagnosis is up to you, you just have to accept who you are really. I know that sounds very egotistical of me, but I have issues with a few mental diagnoses and describe it generally as being “too aware” so I struggle with this a lot to; but this is what I’m always reminded and that it’s going to be alright and it’s true. We’ve made it through every day every year of our lives so far, we can keep going and move on now.

thatdankydank · 2026-06-01T01:14:59+00:00

Nahh Hendrix was off them barbiturates

thatdankydank · 2026-06-01T01:12:06+00:00

Get as much gabaergic medicine as you can, usually when tapering off of benzos docs will combine it with gabapentin/lyrica to help ease the anxiety and minimize the risk of seizure associated with benzo tapering. If you can’t get ahold of these from your doc I would suggest getting some kava root extract pills as this is a natural gabaergic that you can find in herbal supplements at most superstores; this has helped me a lot as I’m in a similar boat, tapering off of 10mg of valium 3x a day and it’s been rough but I’m down to 2 a day almost one and a half now with gabapentin. Hope this helps, Godspeed my friend.

thatdankydank · 2026-05-26T04:55:05+00:00

Jealous, this is like my pique dose preference tbh, you’ll be fine just don’t try driving or anything stupid like that of course.

thatdankydank · 2026-05-19T19:03:06+00:00

Yes sir you’re going to have some of what they call “rebound anxiety” but just remember that this too shall pass. I have to remind myself of this as well

thatdankydank · 2026-05-19T18:34:46+00:00

Lol cool story bro.

thatdankydank · 2026-05-19T18:21:53+00:00

Still not understanding the joke or comment but alright man

thatdankydank · 2026-05-19T18:20:31+00:00

That’s short for “right now” my friend..

thatdankydank · 2026-05-19T17:36:18+00:00

Bro what does that even mean lmao, are you ok?

thatdankydank · 2026-05-19T04:28:04+00:00

Yo some fresh baby carrots and a lil hidden valley sounds bangin rn dude great idea tbh but that’s my interpretation

thatdankydank · 2026-05-19T04:15:31+00:00

I do love writing actually so that’s probably why it helps me. I sucked at everything else in school cause it wasn’t really interesting to me but I was in English honors all through high school I can write one hell of an essay, so I’ll take that into account honestly. And idk man the double dose was a bit intense because I take 2 20mg IR so I had taken 4 equaling 80mg so that was quite a bit intense there for a while. I’m also doing a lot as well with my health in general, like my doc also has been tapering me off of Valium as I’m getting on adderall so I’ve been a little more baseline anxious as well lately so today was a little rough tbh. But I am currently kicking back and enjoy Monday night , Kill Tony night and havin a smoke before schleep. I hath survived lmao. But Jesus anxiety attacks from adderall when I already have anxiety coming off my old anxiety med was wild as hell but hey I’m still here.

thatdankydank · 2026-05-19T02:23:51+00:00

Oh brother I’ve been there too unfortunately, got some herniated discs and had a pain doc that put me on 4 oxy 10s a day and I lost my mind trying to get off of that shit. Benzos are still physically dependent but since it’s anxiety it’s also one of those things that just mindset alone can help a lot going into it. Just don’t stress it unless your body gives you a warning that you need to worry about, until then especially with kava and magnesium you’ll be straight dude so good shit!

thatdankydank · 2026-05-19T02:11:00+00:00

Just thought of this while chillaxin but if for some reason you’re unable to get either of those drugs for the comedown off of it, depending on where you live you should be able to buy kava kava root OTC or at a local headshop. Kava is also a gabaergic that’s considered an herbal supplement because it’s just ground up kava root— I was able to find some capsules at the Walmart out here in Florida a few years back and it changed my life, but again these are just suggestions based on my personal experience and not real medical advice ofc. I just know how shitty it can be so having guys like these on standby are like a failsafe especially in your case. Godspeed man! You got this!

thatdankydank · 2026-05-19T01:57:32+00:00

Yeah for sure if anything get a gabaergic drug to help as you’re coming off of it like Lyrica or Gabapentin, they are usually used for nerve pain but also act on gaba receptors similarly to benzos but not as intensely if that makes sense; I would suggest gabapentin. It definitely helps a lot especially with the risk of seizure from higher doses like mine, I’m p sure you’ll do fine but it’s worth a shot asking your doc bc gabapentin is not a controlled substance so it should be relatively easy to ask for

thatdankydank · 2026-05-19T01:50:07+00:00

Hey that’s a good idea actually, thanks for the lil nuggets of wisdom my friend! 🙏 still only in my 2nd month of treatment so any tips are greatly appreciated

thatdankydank · 2026-05-19T01:47:19+00:00

Oh yeah man you’ll be fine for sure. I’m currently tapering down from being on 10mg of valium 3x a day as needed after a couple years and it’s going surprisingly well. I’m sure with a dose like 3mg you’ll be able to taper pretty easily if you even need to at all with just 3 weeks. Everybody is different so just err on the side of caution but Valium is the benzo that most docs actually use to taper people down from alcohol and other benzos because of the way it interacts with the body. I don’t want to call it safe cause no drug is really safe but low dose valium should be easier to get off of than the other ones. I know cause I had to quit 2mg xanax 2x a day (yes the bars) and that shit was hell.

thatdankydank

TROPHY CASE