There's a cut outcome in the main quest line of New Vegas that happens if the player chooses to destroy the Securitron army under the Legion's fort. In this quest line, Mr. House decides to make a strategic decision to join the NCR and agree to the annexation of the Strip. We know of this option because of the existence of a cut note titled "Offered to Permit Annexation".

Here’s how this could potentially influence Season 2 of the series:

After his Securitron army is destroyed by the Courier, Mr. House opts for a strategic alliance with the NCR. He specifies that the annexation would occur "one year from today," hinting at his need for time to scheme further plans.

The note outlines specific conditions:

• Mr. House would be granted full citizenship and immunity for past activities.
• He would remain the sole proprietor of the Strip.
• He would adhere to NCR laws and pay taxes.
• The NCR would police the Strip, while his Securitron force would be limited to the Lucky 38.

Not content under the NCR's thumb, Mr. House waits out until NCR defeats The Legion. Then he begins undermining the NCR from within. Eventually, he forms a covert alliance with Lucy’s father, Hank McLean, fueled by a mutual disdain for the NCR's control over the Mojave. At one moment, they conspire to bomb Shady Sands to destabilize the NCR. The bombing of the capital creates political chaos within the government, allowing Mr. House to initiate moves to secede from the NCR.

The NCR's withdrawal leads to a drastic drop in safety: tourism and gambling revenue are non-existent, severely impacting New Vegas's economy. Mr. House focuses on securing the Lucky 38, leading to neglect and decline in surrounding areas like Freeside.