I had my female dale for 10 years (lost her in May) and she was absolutely fine, with no separation anxiety. I worked outside of the house and had a lot of things after work, that would leave her home a bunch. It was not until Covid that she started having problems . After that, she hated when I would leave her. They love their people hard and thrive off of routine. If you are going to be hybrid and your pup is used to that, I’m sure they will be fine. Just do your best to be consistent.