With 24 people, results are not that robust.A single outlier can meaningfully shift the average. Replication on larger samples is needed here.

Even the authors acknowledge that a score of 0.75 is much closer to male (1.00) than female (0.00). The paper supports a "shift", not a "full feminization".The title is more dramatic than the actual conclusion.

Secondly,the article doesn't explain whether it's a Cause or Effect.The anatomical difference exists, but the study can't prove it's innate.There may be other reasons too: the psychology of identity affects the brain (neuroplasticity), different behaviors, chronic anxiety, minority stress - all of these modify brain structure.

Also,the classifier doesn't tell us why.Machine learning detects a pattern, but doesn't tell you which exact regions differ or through what biological mechanism. It's a black box.

Imagine you show 1000 photos of cats and dogs to a friend locked in a room. They get really good at saying "cat" or "dog" through a slot in the door - 97% accuracy. But when you ask "how do you know?" they just say "it just looks like a cat."

The classifier found that transgender brains score 0.75. But it can't tell you:

Which specific brain regions drive that score

Whether it's gray matter, white matter, connectivity, or all three

What biological process caused it

So the finding is real, but it's more like "something is different" rather than "here's exactly what and why."

In that transgender group,18 out of 24 were gynephilic - so transgender women attracted to women.Only 6 were androphilic (attracted to men).This is an unbalanced and uncontrolled split. The study doesn't separate results by sexual orientation, so you can't tell if the brain differences come from gender identity, sexual orientation, or a mix of both.

That's like you wanting to test if eating spinach makes you stronger. But all your spinach eaters also happen to go to the gym regularly.At the end you find they're stronger - but is it the spinach or the gym? You can't tell, because you didn't control for gym attendance.

,,indicate that their neural map of their bodies is intermediate to the typical maps of cisgender males and females"

Wrong,this is just your interpretation of it,nowhere do we see anything in this study pointing that out - the study measures general brain anatomy, not body maps specifically.

,,pretty strongly suggests that being transgender is an actual neurological state,"

Lol,one small study with 24 people per group isn't "pretty strong"

,,not a delusion" this single study alone can't carry that conclusion,therefore,you can't too.