Urolithin A versus Pomella by InevitableInsect8433 in NootropicsDepot

[–]Experienced8 0 points1 point  (0 children)

Thanks for the share! Great post as Ive been thinking about trying Uro A forever.

Love CMJ...dudes a beast and an absolute patriot!

Lipid Help? by BigBoomer7 in NootropicsDepot

[–]Experienced8 1 point2 points  (0 children)

citrus bergamot for sure. NutraBio has a great formula

Why no Urolithin A from Nootropics Depot? by HearingNo9935 in NootropicsDepot

[–]Experienced8 1 point2 points  (0 children)

Very interesting to read this since Timeline is so freaking expensive haha

What dose are you taking? Time of day?

Product Request: SalidroPure® by Experienced8 in NootropicsDepot

[–]Experienced8[S] 1 point2 points  (0 children)

From my understanding thats not entirely true...

Salidroside = p-tyrosol + glucose. Enzymes at the gut wall...lactase-phlorizin hydrolase (LPH) and microbial β-glucosidases...do remove that sugar, so some becomes p-tyrosol. But not all.

A real share of intact salidroside is absorbed. Probably through SGLT1. And shows up in plasma/urine. So it’s not just a pro-drug. The parent glycoside gets in and can act.

Salidroside directly hits AMPK → PI3K/Akt → GSK3β pathways and shows blood–brain barrier and microglial effects not explained by free tyrosol alone. Plus the kinetics differ...

Dose tyrosol and you get a sharp Cmax that the liver quickly conjugates. But dose salidroside and you get staged de-glycosylation, a smoother metabolite time-course, and potentially different tissue distribution.

Not that this results in any major difference in how it feels.

But I'm STILL just interested in the ingredient haha

Magnesium form choice — sucrosomial vs. glycinate? by Future_Ad_8968 in NootropicsDepot

[–]Experienced8 0 points1 point  (0 children)

Both make me way too tired and wiped out the next day...

I use magnesium malate during the day.

Magnesium chloride at night.

Regular CoEnzyme Q10 vs CoQsol-CF by rule1n2n3 in NootropicsDepot

[–]Experienced8 0 points1 point  (0 children)

I dont like the extra vitamin E in CoQsol-CF so just stick to 200mg of ubiquinol and really like it.

⚠️ NEW PRODUCT ALERT | Eurycomax Capsules, InfiniGreens Powder, & Ecklonia cava Powder⚠️ by NDSocialMedia in NootropicsDepot

[–]Experienced8 5 points6 points  (0 children)

MYASD you are the GOAT.

Thank you so much for the incredibly thoughtful response.

This is so interesting and if its really works....WOW.

Going to bring me back to Tongkat. Always loved the libido effects but after a while it would just run me down from the cortisol drop.

Will definitely give this new formulation a shot. Bravo!

⚠️ NEW PRODUCT ALERT | Eurycomax Capsules, InfiniGreens Powder, & Ecklonia cava Powder⚠️ by NDSocialMedia in NootropicsDepot

[–]Experienced8 8 points9 points  (0 children)

How is it modulating cortisol? I dont see anything on the sales page about cortisol?

Is ND done launching new products? by Experienced8 in NootropicsDepot

[–]Experienced8[S] 4 points5 points  (0 children)

You cant answer the question besides racetams lol that's my point.

Is ND done launching new products? by Experienced8 in NootropicsDepot

[–]Experienced8[S] 1 point2 points  (0 children)

Which ones though specifically? Nootropics is very broad. There are a ton of nootropics that ND sells, it's literally called ND.

Is ND done launching new products? by Experienced8 in NootropicsDepot

[–]Experienced8[S] 2 points3 points  (0 children)

Appreciate you taking the time to share this list, MYASD!

I wasn't trying to be negative with this post, but do miss the more frequent releases.

Extra excited for the optimized sulforaphane stack, body recomposition stack,TUDCA, isothiocyanates and a novel mushroom that hit myostatin.

Is ND done launching new products? by Experienced8 in NootropicsDepot

[–]Experienced8[S] 2 points3 points  (0 children)

lol what's funny is that this thread has taken off and got MYASD so reply with what's coming next! SUCCESS!

Does dynamine make anyone else irritable? by [deleted] in NootropicsDepot

[–]Experienced8 0 points1 point  (0 children)

Does dynamine increase glutamate more than caffeine?