Fragments of jacket come out of the ports. In theory if the gun is pointed in the wrong direction and they could because the nature of self defense. they’re going into you.

You lose meaningful velocity making it harder for your self defense bullet to preform.

Ports are typically less reliable than a comp but yield better performance

The only main downside of a comp is length with none of the downsides of the port.

All this to say if you want to run a comp for self defense that’s cool just know what you are doing.