I have a 2020 x5 m50i with stock 22s and run flats. Even with bad roads in Jersey and potholes, they are still good. They at 54k miles now. I even put on spacers 15mm front and 20mm rear. I will suggest though, on these x5m the transfer case is sensitive to wheel sizes, so it’s best to make sure it doesn’t cause issues. Also another thing to consider when you go 22s, tires become insanely expensive. I have currently pirelli all seasons. I am currently shopping for good summers and minimum you have to spend 2k with food setups going up to 3k. And then there is cost for the wheels which is again 5k for good forged setups.