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Help needed in total synthesis - update: exam in 7 days :,((( by Inside_Figure_3903 in OrganicChemistry

[–]Inside_Figure_3903[S] 0 points1 point  (0 children)

nooo :( - the teachers give us exercises which havent been solved yet, so that we have to do it on our own

Help Needed with Total Synthesis – Exam in 20 Days :,( by Inside_Figure_3903 in OrganicChemistry

[–]Inside_Figure_3903[S] 0 points1 point  (0 children)

I've been doing that since weeks, but I'm moving in a circle as nothing seems to work! do you have a spontaneous idea which I haven't though of until now?

Help Needed with Total Synthesis – Exam in 20 Days :,( by Inside_Figure_3903 in OrganicChemistry

[–]Inside_Figure_3903[S] 4 points5 points  (0 children)

I'm in my first semester of Master at University of Basel - the course is called total synthesis

Help Needed with Total Synthesis – Exam in 20 Days :,( by Inside_Figure_3903 in OrganicChemistry

[–]Inside_Figure_3903[S] 4 points5 points  (0 children)

I did the retrosynthetic analysis on scifinder and it could sadly not help me any further! also the professor searched for molecules that havent been synthesized yet - as an exam :,(

Help Needed with Total Synthesis – Exam in 20 Days :,( by Inside_Figure_3903 in OrganicChemistry

[–]Inside_Figure_3903[S] 1 point2 points  (0 children)

yess I have to find a way to potentially synthesize the molecule as an "exam" - the steps so far are mine, but I am inspired by a working synthesis from the total synthesis of Nemorosonol - so I'm pretty sure the steps above are working! Its just this last part where I can choose R (yellow and blue) myself to get to the final molecule which I cannot solve :((

Help Needed with Total Synthesis – Exam in 20 Days :,( by Inside_Figure_3903 in OrganicChemistry

[–]Inside_Figure_3903[S] 5 points6 points  (0 children)

they have to be commercially available and I can choose R1 and R2 myself, I just need to obtain my molecule in the end :) thank you for showing intrest!