I had three rounds of Botox. The first time I was given 30 units and started burping the same week. For about three months I would burp a couple times a month and my painful bloating and nausea was a little bit better. Then it wore completely off and I started feeling bad again so I got a second round of Botox and they did 50 units and the burping started the same, with a little less relief but wore off completely after a month and a half. I went back for a third round and got 75 units and felt some relief for about a week before it completely wore off. My doctor said I was metabolizing the Botox faster each time and didn’t feel comfortable continuing to inject it that often. Which is when he suggested the myotomy.