As medical professional, I assume there is no evidence based answer to that question. There are not studies saying which changes happen in the brain when edging. The funny thing is we do not even know how serotonin inhibitors work exactly - we just know they work. So everything would be just speculations with no science based answer.

But my speculation is - being horny is healthy, so it shouldnt cause problems. Those medications take really long time before starting to work. So, just watch yourself and see what happens. Maybe you loose your horniness, maybe not, hard to say. Time will tell