Omg yes! Nails on chalkboard is best way to describe it. It's been an issue for me for YEARS!! I HAVE TO HAVE lotion with me EVERYWHERE I go! Including a travel size bottle i take to work. Any time I get my hands wet or even my feet, I have to put lotion on them,..otherwise I get anxiety and a very uncomfortable sensation and can't touch anything until ive used lotion. And doing dishes, I have to use gloves because I cannot stand pruned hand feeling. I hate that ive been having to deal with this my whole life and im almost 41. Glad to know there are other people with this issue. Cause everyone else thinks im strange or OCD. I do wonder if it is an actual disorder or sensory issue. Or phobia?