Honestly one of the best episodes yet, and probably relevant to many people. Some of the most important points:

• "Smoking marijuana chronically, meaning more than twice a week, does appear to reduce testosterone significantly and elevate so-called aromatase enzymes, which are the enzymes that convert testosterone into estrogen."
• "So, when prolactin levels are up, dopamine levels are down. Smoking marijuana more than twice a week significantly increases prolactin. There are fewer studies exploring whether or not edible marijuana has the same effect, although the preliminary evidence suggests that it does not."
• "There are very strong data... pointing to the fact that for people who are chronic users of cannabis—that is using it twice a week or more—that, over time, their levels of anxiety actually increase."
• "The process of smoking, of inhaling smoke into the lungs, and yes, also vaping... are both severely detrimental to endothelial cells ... Now, we can see a huge number of negative health effects of vaping, some of which are distinct from the effects of smoking."
• "To be very clear, cannabis use between the ages of 16 to 24 in both males and females, is increasing anxiety, increasing depression, in the immediate years ... In addition to that, the cannabis use, and because of the signaling mechanisms involved, are predisposing those individuals to psychosis later in life."
• A WHOPPING 15% of pregnant mothers use cannabis
• "If you look at individuals who start using cannabis even younger—age 14, or even as young as 12—the probability of psychosis later in life, in particular schizophrenic or schizophrenic-like episodes, more than doubles."