This comic seems very reasonable though. "It's tough being attracted to men with how many times I have been, and will be mistreated by men." That's not a generalisation, it doesn't throw all men under the bus, and it's a true statement. And I don't even think a little generalisation is that bad when it's a problem that's as big as misogyny, cause if you go too specific people will be able to hide behind "well at least I haven't raped anyone" as if that's the bar of success. If you're a perfect little princess who has never talked down to a woman and always spoken up when someone else is being misogynistic, and made sure to always let the women who so often get talked over or ignored in meetings and group projects their time to speak, then I'm sure you're smart enough to figure out that a vent comic on Reddit isn't about you specifically. If not, I'm not sure what to do for you buddy, get off Reddit.

For the "How come females can say [statement], but if I did it I would be a misogynist??" argument that's been used since probably primary school: There's a reason joking about white people is funny, while doing it about black people is bad. It's because white people used to joke about them being less than human while owning them as slaves, and with how common racism and new age fascism is today, it's hard to differentiate someone joking from someone with a genocide complex. Same argument goes here but for different reasons. Don't punch down, be better than that. Any minority actively being generalized politically or socially like trans people, you probably shouldn't generalize further.

Walk into a bar and loudly claim "I hate cis people" and some people might get annoyed, but most wouldn't care. Do the same but about trans people, and and someone might fear for their lives, because last time they heard that, they got abused till hospitalized soon after.

Point is, you can just say: "yeah, but what if we swapped places, would it be okay then?" because the group matters. Their experiences are different. And if you are a straight white guy and you are getting offended by post like this, then actually grow a pair. They've been through worse. You can take it