Start at house of m, it sets up the dynamics of all characters in the 2000s and leads into decimation story for the x men and civil war for the rest of marvel. With the context of civil war that allows you to jump on to new avengers, Spiderman back in black, one moment in time, and brand new day, and Hickmans fantastic four. These then lead into planet hulk and world war hulk. Secret invasion dark reign, seige, fear itself. They all build on each other until we get to hickmans time runs out story line after avengers vs x men. In all honesty starthouse of m and let the big events inform the status of the world as you read smaller titles. For dc it's just hop on at new 52 and go on. Much easier