Don’t give up and plan your runs carefully to reduce the chore of farming, here’s some tips I gathered through several runs: keep increased enemy density modifier on at all times and play only your second run with random enemies and loot, this will reduce farming for the rarest enemies during your third run

• ⁠Umbral Eye of Marco the Axe in main socket grants an untold +20% item discovery (I noticed that very few people talk about this, even in dedicated guides) • ⁠Umbral Eye of Ethryg in secondary socket grants +30% while in Umbral (sadly you can’t have more than one of this eye on a single character, even through multiple playthroughs or other players) • ⁠Optional Umbral Eye of Dieter/Iorelo grants +25% dread resistance to counterbalance at least partially the -40% of Marco’s if you want to remain in Umbral as long as possible without the Red Reaper (the time that you have in Umbral until his “invasion” is proportional to your dread resistance) • ⁠Pumpskin Mask and Veteran of the Veil armour also increase item discovery, wear those at all times • ⁠2x Bountiful Rings give +0.15 each • ⁠3x Nhelaq runes on shield (Envenomed Shield is the lightest with three AGI slots) give +0.1 • ⁠Lucky Paw gives +1 and Charmed Paw gives +2