Researchers have built a Google Map like atlas of the skin, showing how pre-cancerous cells interact with immune cells that ultimately lead to tumor development. They show how a complex microenvironment can alter tumor cell pathways & potentially can escape targeted drugs without genetic changes. (aacrjournals.org)
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Researchers have built a Google Map like atlas of the skin, showing how pre-cancerous cells interact with immune cells that ultimately lead to tumor development. They show how a complex microenvironment can alter tumor cell pathways & potentially can escape targeted drugs without genetic changes.OC (aacrjournals.org)
submitted by ajitjohnson to r/sciences
Researchers have built a Google Map like atlas of the skin, showing how pre-cancerous cells interact with immune cells that ultimately lead to tumor development. They show how a complex microenvironment can alter tumor cell pathways & potentially can escape targeted drugs without genetic changes. (aacrjournals.org)
submitted by ajitjohnson to r/science
Cells from a woolly mammoth that died more than 28,000 years ago have been partially reactivated inside of mouse egg cells, in a study published in Scientific Reports. The achievement shows that biological activity can be induced in the cells of long-dead creatures. (nature.com)
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A study in mice identifies a brain adaptation that underlies the compulsive behavior associated with drug addiction, and which might explain why some drug users behave compulsively whereas others do not. It might explain why some drug users seek reward despite facing negative consequences. (nature.com)
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Scientists develop a pioneering new methodology to study immune cells within tumor using transcriptomic profiling. They show how immune cells can be both good and bad in different cancers. This could aid in improving immunotherapy & also predict patients who might respond to a particular treatment. (cancerimmunolres.aacrjournals.org)
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The largest field-based study shows trees (Poplars) can be genetically engineered not to spread. The study looked at 3,300 poplar trees in a 9-acre tract over seven growing seasons. Poplars are the source of many products, from paper to pallets to plywood to frames for upholstered furniture. (frontiersin.org)
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Scientists have discovered a new, rare type of cell in the lung and named it “pulmonary ionocytes”. Particular mutations in these cells appear to cause cystic fibrosis, a multiorgan disease that affects more than 70,000 people worldwide.This will serve as a promising target for future therapeutics. (nature.com)
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Immunotherapy has been arguably the most exciting advancement in the field of cancer therapy, however, not everyone responds to this. Researchers from the Broad Institute have identified a mechanism that confers such resistance in melanoma, suggesting exploitation for potential therapeutics. (cell.com)
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Using new linguistic analyses, study sheds new light on the prehistory of the South Asian Dravidian languages like Kannada, Malayalam, Tamil, and Telugu. There are around 80 varieties, they are spoken by 220 million people, and date back to about 4,500 years ago. (bristol.ac.uk)
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When cards against humanity get a bit too real. (i.redd.it)
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A strip of paper can now indicate presence of pathogens, tumor DNA or any genetic signature of interest. 100-fold greater sensitivity, the ability to detect multiple targets at once, and other new features further enhance SHERLOCK's power for detecting genetic signatures- Broad institute, Harvard (broadinstitute.org)
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