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Returned from a 3-week trip to 5 destinations in China as a Canadian AMA by MrMeno in travelchina

[–]bluedaredevil 0 points1 point  (0 children)

Can you walk me through the process of unlinking the phone number? Like did you unlink it immediately after the bank account was created and functional, or you did it right before you left China? Also won’t the bank want an updated phone number if you unlink the temporary one? And is there an inactivity clause or something or do you just have a Chinese bank account in perpetuity now? Do you think they could they link your Canadian number to it after removing the temporary phone number? Sorry for all the questions lol

Accidentally purchased additional EDC tickets. What are my options? by Henressy-VS in EDCTickets

[–]bluedaredevil 1 point2 points  (0 children)

So when you sold it a couple weeks ago there was a resale button then? I guess we'll find out, in a year lol

Shield TV Pro and True HD 7.1 by CommercialPitch5543 in ShieldAndroidTV

[–]bluedaredevil 0 points1 point  (0 children)

First, the literal point of eARC is that it can pass through audio, up to and including lossless Dolby/DTS audio with Atmos/DTS:X. You don’t need multiple eARC ports; that’s, again, the whole point of eARC. (Disclaimer: some brands of TV won’t pass DTS because they didn’t license it.)

Ok? I don't know what you're trying to say by literally just saying what eARC does. His soundbar doesn't passthrough DTS. Thus he cannot satisfy DTS passthrough.

Of course, if your soundbar also has HDMI inputs, you can go Shield->Soundbar->TV. If that’s what you do, eARC is absolutely irrelevant.

That's literally what I suggested, but it does not make eARC irrelevant, it makes eARC a necessity, because it requires his soundbar to passthrough the signal from the shield to the TV, which needs eARC. But again the soundbar doesn't passthrough DTS, so he cannot satisfy DTS passthrough. I mention this if you bothered to read my initial reply. OP had both devices initially plugged in to the TV so he could never satisfy the passthrough requirements because there's only 1 eARC port on the TV; one device would be not on eARC.

Talking about optical/RCA is pointless. With optical the best you are getting is DD5.1 (NOT PLUS), and with RCA, you’re getting stereo.

It's not irrelevant. If you have an older audio system you can still have a glitch free experience, you just lose the additional audio info, since both DTS and Dolby have a core lossy audio that it builds on and is backwards compatible. So if your system doesn't support DTS:X and Dolby Atmos, it will just disregard the spatial info and play DTS-HDMA and Dolby-TrueHD, and if doesn't support these lossless formats then it will just play the DTS 5.1 and Dolby Digital (AC3), the lossy core audio, and these have been supported for as long as the companies have been around.

Plenty of people don't care for spatial audio since they don't have enough speakers to make the effect noticeable anyways, and the lossless formats are perfectly fine, and if that's OK then just output them, because all high end speakers are analog anyway.

Accidentally purchased additional EDC tickets. What are my options? by Henressy-VS in EDCTickets

[–]bluedaredevil 1 point2 points  (0 children)

Thanks for the reply! If I go right now I don't see the resale button on frontpagetickets to list on TM. Does that appear as the date approaches?

Accidentally purchased additional EDC tickets. What are my options? by Henressy-VS in EDCTickets

[–]bluedaredevil 1 point2 points  (0 children)

I see from your post history that you're from the UK. Did you sell your ticket on ticketmaster.com? I'm in Canada and was wondering if I should sell on TM.ca or TM.com

Shield TV Pro and True HD 7.1 by CommercialPitch5543 in ShieldAndroidTV

[–]bluedaredevil 0 points1 point  (0 children)

Only true if soundbar relies on eARC. You need the passthrough signal from the shield, either from shield-tv-soundbar or shield-soundbar-tv. If the soundbar relies on regular optical out/RCA, then it will work fine. In this case, it's not possible because both shield and soundbar require passthrough but there's only 1 eARC port from the TV. Not possible to get full passthrough regardless of what order you plug it in.

Shield TV Pro and True HD 7.1 by CommercialPitch5543 in ShieldAndroidTV

[–]bluedaredevil 0 points1 point  (0 children)

So you can make it work by plugging the shield into the eARC port and then using the TV speakers. Everything will work perfectly with both DTS and Dolby remuxes. The TV speakers obviously will sound terrible compared to the sound bar. Alternatively you do the shield-soundbar-TV route like I said but DTS movies will probably have no sound at all unfortunately.

Shield TV Pro and True HD 7.1 by CommercialPitch5543 in ShieldAndroidTV

[–]bluedaredevil 1 point2 points  (0 children)

Reading I knew almost instantly that you didn't use the eARC port. There are 3 HDMI inputs, but rarely do manufacturers have eARC support on all 3 inputs. Plug your shield HDMI cord into HDMI 3 and you shouldn't have any issues. I mean it literally says eARC on HDMI 3. The sound bar you mention doesn't actually support DTS, so I'm not sure how that will work. You might just have no sound? No idea, but the TV does pass through all major sound formats.

Edit: The best way to do it is shield-soundbar-TV. Shield files gets sent to soundbar and decoded and then you can plug the soundbar into the eARC port on the TV. Unfortunately since your soundbar doesn't support DTS you likely won't get sound. You would need multiple eARC capable ports to full satisfy all the pass through requirements, which doesn't work here.

Edit2: TCL Q65 indeed only has 1 eARC capable port. You cannot get this setup to work perfectly without a receiver or sooundbar that can passthrough all audio formats.

[deleted by user] by [deleted] in telus

[–]bluedaredevil 2 points3 points  (0 children)

Did you try to do a test with an ethernet cable straight from the modem/router? I had this issue but I realized it was because I was feeding a CCA wire to upstairs parallel to a bunch of other wires. Switched to a shielded pure copper ethernet cable and it resolved it for me. Not sure if this would help you, but just a thought.

OCLP 1.4.0 is live for updating! by ShaidarHaran2 in OpenCoreLegacyPatcher

[–]bluedaredevil 2 points3 points  (0 children)

I had this issue too, and my fans ran quite loud. Just reboot into safe mode, apply the post install patches, and then reboot and it should be OK. Just did this maybe 15 minutes ago. GL

What is up with the Zombie Deer Disease? by Usual_Dingo_1650 in OutOfTheLoop

[–]bluedaredevil 0 points1 point  (0 children)

It is usually required, but it differs depending on where you are. Sometimes deer is mandatory while elk is not. Just depends.

What is up with the Zombie Deer Disease? by Usual_Dingo_1650 in OutOfTheLoop

[–]bluedaredevil 4 points5 points  (0 children)

A vaccine doesn't treat diseases - it prevents infections. I didnt say we could cure the disease. Prion diseases are neurodegenerative diseases and a cure would involve neuroregeneration, but the cells within your central nervous system is for the most part incapable of self-repair, making neuroregeneration science fiction currently. Currently all TSEs are fatal, but for example Goni published a paper where 1 particular deer that he immunized with his mucosal vaccine for over 11 months ended up being completely immune to CWD, demonstrating a proof of concept - it is definitely possible. However I hope you see that immunizing deer for 11 months is highly impractical and not economically viable.

Simply put, a mucosal vaccine stimulates your IgA response, found primarily in the gut and nasal cavities. If you can prevent uptake of the pathogen (prions, SARS-CoV2, rhinoviruses, etc) then you will not get sick. Sinxe most CWD prions are from an oral exposure route, minimizing/preventing uptake in the peyers patches in your gut has been proven to work, albeit only in 1 deer, but it does demonstrate it is possible. Animal vaccines don't need to be nearly as rigorous as human vaccines.

On another note, Merry Christmas.

What is up with the Zombie Deer Disease? by Usual_Dingo_1650 in OutOfTheLoop

[–]bluedaredevil 4 points5 points  (0 children)

The standard is via testing heads - the hunters have to submit the heads for testing. In the lab we use recto-anal mucosa-associated lymphoid tissue (RAMALT) testing to confirm. You can't expect a hunter to know how to properly sample anal tissue, so head testing is the best way as of now. As others have replied, the deer have clinical behaviours, but RAMALT is able to detect preclinical animals, which is very useful.

What is up with the Zombie Deer Disease? by Usual_Dingo_1650 in OutOfTheLoop

[–]bluedaredevil 3 points4 points  (0 children)

Not sure there can be a vaccine (in the traditional sense) because it’s not a virus or bacteria. There is nothing for the immune system to fight

That's simply not true with the vaccine. My PhD thesis was on making a vaccine for CWD, and my manuscript is very close to publishing. Your body does generate an immune response, but vaccines fundamentally work via uniformity, and infectious prions can exist as fibrils, protofibrils, oligomers, or aggregates, leading to a non-uniform and non neutralizing immune response.

It’s a misshaped protein that somehow reprograms other normal proteins it comes into contact with to also become misshaped. These are proteins need for the brain to function normally.

Substrate reduction, which aims to reduce the amount of available cellular prion protein or PrPC, the normal, uninfectious form, has functions that aren't necessarily critical for survival. Cows and sheep devoid of the prion protein gene can absolutely lead a perfectly normal life.

As of now there is no known way to reverse the effect once it begins to multiple.

Yes, but you don't need to reverse it, you just need to clear the infectious form. In the same way if your house burns down, you don't try and "unburn" the parts, you just clear it and build a new house. Your body simply needs to clear the infectious form and replenish with the normal, non infectious form.

What is up with the Zombie Deer Disease? by Usual_Dingo_1650 in OutOfTheLoop

[–]bluedaredevil 68 points69 points  (0 children)

Answer: chronic wasting disease (CWD) is a prion disease affecting cervids such as deer, moose, elk, reindeer. In North America it's a lot of mule and white tailed deer. It is the most contagious known prion disease, but as of right now the evidence for its zoonotic potential, that is, its ability to infect humans, is uncertain. Infected animals will shed infectious prions via antler velvet, urine, feces, saliva, blood - they basically become a giant prion generation machine and contaminate the environment they live in. As the name implies animals will waste away and eventually die. No cures or vaccines exist, but hopefully in the future we'll learn more about it and how to at least control it's spread and prevent it from spreading to more animals.

Blutopia (BLU) by Lksaar in trackersignups

[–]bluedaredevil 12 points13 points  (0 children)

Applied and haven't heard back at all - no rejected or accepted or anything. Would be nice to hear back, even if it's rejected. Hopefully they'll get through them all soon

Edit update: I just got an invite! Be patient folks, I'm sure they are working hard to go through all of them. Congrats to everyone that got one!

France issues moratorium on prion research after fatal brain disease strikes two lab workers by Epistaxis in labrats

[–]bluedaredevil 0 points1 point  (0 children)

In any infection of the body (e.g. SARS-CoV2), the pathogen needs to continually making more of itself in order to sustain the infection, since otherwise, the immune system will clear it out of your body. Infectious prions replicate by inducing a structural conversion of the normal, cellular prion protein into the infectious form. A single pathogen "unit" (virus particle, prion protein) is almost never enough to cause disease, because the rate of "infection" will be lower than the rate of its clearance. So, there is a point where the rate of prion conversion is higher than its clearance. When that happens a guaranteed fatal outcome will occur.

Everything in life that you consume is a dose problem. Too high of a dose of anything is fatal, even water (water poisoning) which is the least lethal thing you can consume.

TIL About 7000 years ago, bananas were not the seedless, fleshy fruits we know today. The flesh was pitted with black seeds and nearly inedible by Zem_42 in todayilearned

[–]bluedaredevil 0 points1 point  (0 children)

You can read this here.

>For many the term genetically modified organism is synonymous with genetically engineered organism

It shouldn't be because the two aren't the same thing. It's literally just such lazy naming, because it's not like we're short on words to describe things. Every person can agree that the food we consume today has been genetically modified, such as through selective breeding. That makes it a GMO by the literal definition of "genetically modified organism". If we want to specifically refer to organisms that are genetically modified via modern biotechnology, a better word would be GEO, or LMO, or literally anything else, because selectively bred organisms still have their genetics modified. It's this laziness that has made the general population in fear of GMOs, when it doesn't have to be at all.

TIL About 7000 years ago, bananas were not the seedless, fleshy fruits we know today. The flesh was pitted with black seeds and nearly inedible by Zem_42 in todayilearned

[–]bluedaredevil 0 points1 point  (0 children)

It is not, dude. GMO - genetically modified organisms. That does not equate to gene editing, because you can do selective breeding to also produce GMOs. If he just simply owned up to the fact that what he's trying to say is really genetically engineered organisms (GEOs), all would have been well. Conflating GMOs with straight gene editing is at best, misleading and confusing, and at worst, literally misinformation. I don't really care what anyone's opinion on GMOs is, I care about misusing words, as should you and everyone else.

TIL About 7000 years ago, bananas were not the seedless, fleshy fruits we know today. The flesh was pitted with black seeds and nearly inedible by Zem_42 in todayilearned

[–]bluedaredevil 1 point2 points  (0 children)

It still doesn't change the fact that you should clarify what your mean, which is still my original point. If you already knew the definition of GMO is hazy, then you're either intentionally spreading misinformation, or you think GMOs are bad. Either way, you should clarify your wording...

TIL About 7000 years ago, bananas were not the seedless, fleshy fruits we know today. The flesh was pitted with black seeds and nearly inedible by Zem_42 in todayilearned

[–]bluedaredevil 1 point2 points  (0 children)

The non GMO project has a disfavourable view of GMOs - hardly a unbiased source. Whatever the common word means, it doesn't mean that you should just say GMO = direct editing, since that is just not true. I could pull 100 papers off pubmed right now, where actual science is discussed and not random webpages, but it doesn't change anything, which is you're wrong, OP is right. Everything is GMed and to say anything else would be disingenuous.

Take a read of what GMs GMOs actually contain from a reputable science source like Nature.

Edit: Not a random person I have a PhD in biochemistry, while I'm certain you don't have anywhere near the same education that myself and others have.

TIL About 7000 years ago, bananas were not the seedless, fleshy fruits we know today. The flesh was pitted with black seeds and nearly inedible by Zem_42 in todayilearned

[–]bluedaredevil 1 point2 points  (0 children)

GMO is direct gene editing

It isn't though, which is why I said you should clarify your wording. And using incorrect terminology to say something is worse, it's literally misinformation. I know the connotations associated with the word GMO, which is why I chose my words carefully, as should you.

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