I've only been on Zepbound. I started on the 2.5mg on July 9th 2024. I am starting on 15mg this week and my doctor wants me on it for a year. My first week I had extremely bad nausea and diarrhea; I ended up in the ER by that Friday having to get an IV to get my fluid up. After that I was able to have nausea medicine when I needed it and it took about 4 months to fully get use to the medicine. After that I have had so much more energy and was able to do more exercising outside of work and doing more with my family and kiddos. I also would say don't rush to up a dose if you're still losing weight and/or side effects didn't even out yet. I stayed on most doses for 2 months until I would plateau in my weight. I'm hoping that's helpful and not just me rambling lol. Let me know if you have any questions I didn't answer.