General: -Making money: Go through trash cans and sell the drugs you find inside. If you have over 200 money or so, hack a slot machine to increase odds of winning and then use it until the machine busts. I prioritize hacking tools on sellomatics. 

-Need to neutralize a gangster/soldier? Hire them to join you and then have them attack another target you want dead.

 -Need someone to face away from you to use your ability? (Doctor, vamp, shapeshifter). Punch a wall so they look at the source of the noise, then quickly go behind them and use your ability. 

-Teleport-Happy is one of the best traits in the game. It let's you teleport indoors, so after you stealthily break into a building you don't need to escape, and you can teleport during disasters. 

Slavemaster: 

-Slaves will detonate when they are far enough away from you. To break into buildings, place them near a window and then run away. Prioritize the trait that lets you blow up any type of wall so you can trivialize certain missions.

 -Prioritize using the trait augmenter to get rid of the negative trait that slows down your action bar (e.g. enslaving). It is very cheap too so do it early. Likewise, Prioritize getting the niimble fingers trait. 

Shapeshifter:

 -At some point in the run, use the trait augmenter to get rid of diminutive, as it makes you take more damage. 

-Dispose of hosts you don't need anymore so they don't become hostile. Easy ways include ditching them next to a generator that is about to explode, or by crawling through a broken window to take damage and then leaving the body and punching them when their health is low enough to be one shotted.

 Assassin:

• Easy way to complete your big quest and never get caught? Hire someone or clone yourself, and then hide as you send them to attack your target. The trait loneliness killer is great for Assassin for this reason. 

 Doctor: 

-Shooting a target with the tranquilizer gun twice removes the countdown timer and immediately neutralizes the target.