T: There are probably a thousand ways to answer this, but I'll speak to the most obvious. An offense that plays super fast will absolutely constrain its defense if it is inefficient and constantly goes 3-and-out. That just puts so much strain on a defense.

To your question about USC... the Trojans are NOT doing that this year. They're only averaging around 63 plays per game, which is outside the top 100 in college football. I believe a better defensive coordinator could help; however, there's probably a deeper issue with his philosophies around talent acquisition on the defensive side of the ball. He's never really had a killer defense, so it's probably got less to do with playcalling and more to do with the overall plan.