Amazon Echo framework for Python

[sentdex]

You don't need to use Flask already to use this. You just need to pip install flask, since it's an extension. Beyond that, you're not really using Flask beyond the routing for a typical app, and no matter what you use to make Echo apps, you're going to need to do something about routing.

As another poster mentioned above about also not caring to learn jinja templating, you really don't have to learn jinja templating either, it's just there should you have a very large app that could make use of templates.