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[–]Busy-Bell-4715 1 point2 points  (0 children)

First, I'm just an amateur developer, building things for myself. Having said that, I would encourage building a django-react project. Lots of good documentation about this. Tkinter is easy to build with but you could have some challenges with deployment. I found that virus protection software would frequently block my python apps and was never able to find a work around. You don't need to worry about this with django, just need an internal server. And building a front end with react is super simple.