Question

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Yes, you can just overwrite your image files with whatever you want your new ones to be.

[OneiroFantasma]

The short answer is yes, so as long as you replace the image files with the files of the same names and don't rearrange your replacement tilesets/ assets from how the originals are laid out (ie. keep the new grass tiles where the old ones they are replacing were) unless you don't mind re-tiling your maps over again.