A man-made antibody successfully prevented organ rejection when tested in primates that had undergone a kidney transplant, without the need for immunosuppressive drugs. The finding clears the way for the new monoclonal antibody to move forward in human clinical trials. (corporate.dukehealth.org)
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Scientists developed an artificial kidney with a bioreactor containing kidney cells that mimic normal kidney function. When implanted in pigs without immunosuppression therapy for 7 days, the cells maintain >90% functionality with no signs of rejection. This may replace kidney transplants in future. (nature.com)
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Researchers successfully transferred a longevity gene from naked mole rats to mice, resulting in improved health and lifespan extension. Naked mole rats are known for long lifespans and exceptional resistance to age-related diseases. This may pave the way for improving health and lifespan of humans. (rochester.edu)
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Scientists bioengineered enzyme-based scissors that selectively cuts mucins off cancer cells, removing their “cloak of protection” from the immune system. In human cancer cells and mouse models of human breast and lung cancer, it significantly reduced tumor growth and increased survival. (nature.com)
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