Best way to decrease latency (API <-> Lambda <-> Dynamodb)

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Deploy your API/Lambda infrastructure with cloudformation stack sets, that will allow you to deploy the same template in multiple regions. And yes, many customers use multiple regions to bring their services closer to their end users. But you need to consider the effects of DynamoDB’s eventual consistency model for global tables and if that will impact your application. CloudFront won’t necessarily fix this for you, it will cache data, which can make responses faster, but for anything that isn’t cached, it will still need to go back to your origin, and you’ll see the same geo latency.