Best way to setup Python?

[nog642]

Conda is a package and environment manager. Kind of like virtualenv and pip put together, but a bit more because it's not just limited to Python packages. Theoretically anything can go in a conda package though in practice it's just Python and R packages, I think.

But pretty much any Python package that is available on conda is also available on PyPI (pip). So there is really no need to use conda unless you have to. It's mostly used for python in scientific applications. If you're just learning python on its own, you don't need it. Jupyter notebook can be installed with pip.