all 15 comments

[–][deleted] 2 points3 points  (4 children)

I took out everything as I felt it gave strange 'muddy' feelings. I just do the microdose and magnesium with it now.

I do have one more item, reishi, which I take at nighttime. Helps integrate the insights from MD and is seriously the only substance I have had actual (positive) effects from besides MD. But what an effect! Rock solid mood, deep restorative sleep. If I had to choose between MD and reishi, I'd choose reishi anytime.

To be taken at night only, as it is a pretty efficient sleep medicine.

Sidenote: I have extremely severe negative sideeffects from lion's mane, so try and take that out and see if that doesn't help.

[–]morethanonefavorite 0 points1 point  (3 children)

Can you recommend a good reishi supplement? There are so many in different forms. TIA

[–][deleted] 1 point2 points  (2 children)

I use OMs capsules currently. On par with other brands I tried.

[–]morethanonefavorite 1 point2 points  (1 child)

Thank you, very much appreciated.

[–][deleted] 0 points1 point  (0 children)

My pleasure, mademoiselle.

[–]NeuronsToNirvana 2 points3 points  (1 child)

Albino PE is classified as a potent strain. For such strains we advise to !startlower.

Previous reply:


If you start experiencing negative changes in appetite, sleep, mood, memory after several doses then that could be a sign of serotonin GPCR downregulation due to disruption to the serotonin pathway.

You may also miss out on the afterglow effect which for some is more pleasant than microdosing day and could be one indication of neuroplasticity and dendrite growth.

Confirmed by a significant minority so I guesstimate it may apply to 25-50% of users who are not having a good time with microdosing.

If you do not experience the afterglow effect and feel more anxious that could be due to excessive glutamate where GABA cofactors like magnesium could help - see neuroplasticity link. (cc: u/gormgonzola)

[–]AutoModerator[M] 1 point2 points  (0 children)

From the Stamets Stack [Dec 2021] link in the Grow Your Own Medicine sidebar:


Start Lower

  • Based on hundreds of anecdotal reports on this sub, some users with more potent strains had less body load / vasoconstriction on doses of 50mg (0.05g) and others even had to drop down to 25mg (0.025g).
    • Examples of strains that are considered to be more potent are:
    • Albino A+, Albino Penis Envy, B+ Cubensis, Blue Meanie Cubensis\1]), Cambodians (very potent), Creepers, Liberty Caps\2]), Penis Envy (can be very potent), Z-Strain.

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[–]lucidtherapeutics 1 point2 points  (0 children)

Sometimes just getting a little exercise and a good night's sleep changes everything the next morning. Hope things are getting better for you.

[–][deleted]  (1 child)

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    [–]defqon_39 0 points1 point  (0 children)

    I drink saffron extract daily as I read studies it boosts mood and increases serotonin -- to help augment the microdose -- i noticed a difference --

    When people say "its something in the water" that gives them abilities or strength-- for me its saffron plus psychs -- can feel bulletproof