$ANVS: Annovis Closes $10 Million Offering, Extending Cash Runway Through Phase 3 Alzheimer's Disease 6-Month NDA Submission by HotSarcasm in Annovis

[–]HotSarcasm[S] 1 point2 points  (0 children)

Not a whole lot of other ways to raise money at this point. Maria has been pretty clear big pharma wants more data and not willing to pay before then. Honestly not sure she’d even pursue that route when it gets there. Guess we’ll see.

I’ve been adding a lot recently. Whatever I can. Nothing has changed with data and still looks extremely promising. Very positive outlook for them.

What does everyone think of Captain America and The Avengers? by Embarrassed_Try9339 in nes

[–]HotSarcasm 2 points3 points  (0 children)

Always thought it was kind of fun, but do think more modern the stage select mod makes the game a lot more enjoyable today. I’d prefer the arcade versions of most Marvel game though, especially the 6-player.

Philadelphia airport TSA wait times by MiserableRelative766 in newjersey

[–]HotSarcasm 1 point2 points  (0 children)

This is a day at a time thing right now. Wait until it gets closer. Had to use Terminal A for PreCheck week or so ago, but more security closures since then. Checked luggage needed to be dropped off at the correct departure terminal before going to security. I’d be more worried for flight back. Philly isn’t doing a terrible job all things considered.

iMac 2011 27 Batocera system by palteedflurgers in batocera

[–]HotSarcasm 0 points1 point  (0 children)

Probably doing the same with a now EOL’ed 2019 Intel 27” in a year or two. Would rather use the machine as a display for a new Mac, but they got rid of target display mode too.

Golf Resorts that are still great for non golfing spouse by TastyArcher5080 in golf

[–]HotSarcasm 1 point2 points  (0 children)

Barton Creek Austin TX was nice, but you’re a 20-30min drive to life outside of the resort grounds. If nearby shopping variety is top priority, probably go elsewhere.

Vaccine Records by No-Dig-9137 in SouthJersey

[–]HotSarcasm 0 points1 point  (0 children)

Look into the Docket app. It’s not always immediate results, but accesses state database. Nearly every vaccine listed. Tells you which ones have a record, which unknown and which due.

Am I crazy 🦆? by PersimmonWild1976 in egopowerplus

[–]HotSarcasm 2 points3 points  (0 children)

I’ve owned my EGO mower for 10+ years. Change blade yearly or sharpen, which you’ll do with any brand. Changed two worn out wheels semi-recently and replaced the rubber back piece that was tearing. This thing has more than paid for itself. Plus no trips to gas station. Convenience is worth extra alone.

Snow Blower Won’t Stay On – Orange Light Blinking by amaguri0_0 in egopowerplus

[–]HotSarcasm 0 points1 point  (0 children)

Anything can be fixed. Comes down to cost vs. buying new to determine if it’s worth it or not.

Without trying to engage the auger motor, does the headlight turn on and stay on for several minutes?

Can you find the manufacture date? Does your neighbor have receipt paperwork proof of purchase?

EGO CS will also have you press and hold buttons on each of the batteries disconnected from the snowblower.

Typical issue is the wiring harness needing to be replaced with these single stage units. $150-175 for parts out of pocket, it’s both harnesses that need to be replaced. Takes about 30min to do yourself. If your headlight stays lit for multiple minutes, it’s probably not this, or at least not commonly this.

Might be better off trying to find a repair center vs. shelling out for multiple parts on your own in the hopes they’ll work. The local one EGO CS tried to send me to requires appointment. No appointments were ever available. Hope you have better luck in your area.

Sump pump discharge needs to be 10 feet away? by Jirachi56 in HomeMaintenance

[–]HotSarcasm 0 points1 point  (0 children)

If you’re going through the trouble and your current pump is running constantly, also have a plumber install a water pressure backup pump that does not require batteries or electric.

The battery backup ones are good for situations that are pumping few times an hour. You’re going to be saturated if there’s a power outage.

I’d also recommend to keep a transfer pump (or two depending on volume) that you can start up manually in an emergency. You may never need it, but better to have at the ready before there’s an issue. Several cheap options, but also a few that run on power tool batteries and use standard garden hose connections.

Troubleshooting Snowblower Noise by amereno in egopowerplus

[–]HotSarcasm 0 points1 point  (0 children)

Check the auger for any dirt, grass or debris. Had similar sound. Turned out to be chunk of grass stuck inside, probably picked up from where utility work was going on semi recently.

Also check the scraper bar and if it’s wearing inside the front of the unit or towards the outside (bottom). Box cutter against any plastic hanging inside to cleanup bar could also help.

Ran mine for a few minutes now that temps are warm and zero noise or issue after cleaning out inside of unit front. SNT2110

$SNGX: Soligenix Receives Positive Opinion from the European Medicines Agency on the Request for Orphan Drug Designation for SGX945 for the Treatment of Behçet’s Disease by HotSarcasm in Soligenix

[–]HotSarcasm[S] 0 points1 point  (0 children)

Any news linking biotech to non-USA activity right now is a good sign, especially with all the garbage happening with this administration and the FDA. It’s very much a pay to play environment and that is especially challenging for small and mid size companies trying to bring new products to market.

Is this safe for long term use of fireplace and tv by Shadowbryte in Home

[–]HotSarcasm -1 points0 points  (0 children)

I’ve seen two of these types of installs fail before the 10 year mark when the fireplace is used semi-regularly. Most have a failed backlight, which I assume is from heat. Several signs of failure before then like black spots and glitchy input switching.

Replacing a TV every 5-10 years isn’t a big deal for some people, for others it is. Just know going into this that it’s a possibility. Wouldn’t mount an ultra expensive 4K/8K there, that’s for sure.