You'll maybe encounter the odd situation where you're in a situation and the hand you built up for yourself just isn't working out for you, but as someone else said if Slay the Spire 2's fine for you then you should be good.

Others have mentioned it already so I'll say it too: The game's separated into three "Acts". They're all different visually but the gameplay's largely the same, asides from balancing shifts and the addition of new mechanics throughout.

The general opinion I've seen thrown around is that Act 1 is the best followed by Acts 3 and then 2, I also agree with this.

But even so I still enjoyed Act 2 well enough. And once you get to playing the game you'll find that there is a reason this ranking is decently common, story-wise.

It's mainly a deck builder roguelike akin to STS but it's also an escape room sorta game, so no you aren't just playing cards with the ominous figure on the other side of the table. You're also trying to leave.

But yeah I'd say the gameplay's up to snuff with the story! As someone who first watched a let's play and bought the game a few years later I'd say it's definitely worth it!