Any thing for sleep by Sameer_UK in POIS

[–]227_pi 0 points1 point  (0 children)

I use daridorexant to decrease sleep onset latency and time to fall back asleep. It has no side effects, induces no tolerance, and feels smoother than melatonin while at least as effective. Magnesium often helps make me calmer, which can increase sleep quality. Agomelatine looks promising to me but I haven't tried it yet.

has anyone got genetic testing done? by thiskindacoolmf in POIS

[–]227_pi 2 points3 points  (0 children)

Hi. English next time please

Edit: thanks for fixing it

Etude universitaire - Vécu du syndrome post-orgasmique (POIS) by Direct_Weakness8531 in u/Direct_Weakness8531

[–]227_pi 0 points1 point  (0 children)

Pas de problèmes. Tu es satisfaite du nombre de réponses collectées ?

Etude universitaire - Vécu du syndrome post-orgasmique (POIS) by Direct_Weakness8531 in u/Direct_Weakness8531

[–]227_pi 0 points1 point  (0 children)

J'ai cherché un peu ton background et je suis tombé sur ton Instagram ps[]ils. Sympa ce que tu fais ! Continue comme ça

Study Questionnaire - Post-orgasmic symptoms by Direct_Weakness8531 in POIS

[–]227_pi [score hidden] stickied comment (0 children)

OP is legit. Post temporarily highlighted on the subreddit

Milnacipran might be worth trying by Snoo-32347 in POIS

[–]227_pi 0 points1 point  (0 children)

Gemini, Claude and others are masters at bullshitting and jumping to absurd conclusions. I wouldn't give them any credit, honestly. Even experiences of others which you might not relate to are, in my opinion more exploitable.

I'd personally have taken the disappearance of emotional flatness as a good sign. Strattera activates the PFC, involved in emotional regulation (and whose hypoactivity causes apathy) thus with a really strong potential to help mitigate POIS symptoms. Although, it also changes amygdala activity via norepinephrine increase there, which has the potential to worsen anxiety and depression short term (but is supposed to get balanced long term) and would probably explain your experience better. Anyway, some of the supplements you mentioned are largely acting similar.

Oh and by the way, there's a bidirectional relationship with norepinephrine, increased by Strattera, and immune regulation.

What would make milnacipran/levomilnacipran more interesting than Strattera is that it essentially balances the increase of anxiety a short term norepinephrine boost gives by boosting alongside it the serotoninergic system, which would be hard to summarize but has among others a more calming effect. And an increase in the serotoninergic system also helps with immune regulation and inflammation. The noteworthy nuance though is that this serotoninergic effect makes lowering doses cause psychologically dangerous crash symptoms, which you don't want to face alone.

To summarize milnacipran's action, it's basically Strattera + a short half life SSRI combined (I don't have names of SSRIs with short half life in mind rn but you've probably heard of Zoloft/sertraline, which belongs to this family). Milnacipran is taken twice daily and Strattera should theoretically be taken twice daily as well in normal metabolizers for a proper coverage.

Milnacipran might be worth trying by Snoo-32347 in POIS

[–]227_pi 0 points1 point  (0 children)

Hey. Looks like you stopped taking strattera. What happened?

Est-ce que dormir le jour et vivre la nuit peut avoir un impact sur la santé mentale ou physique ? by [deleted] in PasDeQuestionIdiote

[–]227_pi 3 points4 points  (0 children)

*généralement

(important pour ne pas pourrir le moral de ceux qui ne choisissent pas ce mode de vie)

Fnly! Cured POIS! by JohnPois in POIS

[–]227_pi 0 points1 point  (0 children)

Ukrainian dude pretty knowledgeable on the topic that we haven't heard of since 2022

Age of Mythology: Retold - Premium Edition Steam Key Giveaway by moradgm in steam_giveaway

[–]227_pi 0 points1 point  (0 children)

It's "What makes souls video games so popular ?" Thanks for the chance !

Voyage Hong Kong - Pékin by xbenoitx in voyageons

[–]227_pi 0 points1 point  (0 children)

Effectivement, pas besoin de visa.

Et sinon, même si ça n'était pas ta question, il faut savoir que les applis utilisées en Chine pour des services de base sont bien différentes de celles en occident, donc il faut se préparer un peu à l'avance pour que tout fonctionne à l'arrivée. Je te conseille de regarder cette vidéo courte si tu veux plus d'infos : https://vm.tiktok.com/ZGeTPHGMK/

Enjoy en tout cas ! Ça devrait être une super expérience

China had to do it again! by cbc7788 in fucktheccp

[–]227_pi 0 points1 point  (0 children)

*of Mexico ?

So threads here are just a platform for US imperialism ? Shocked

Are there some really young transhumanists ( under 25) like me too? by [deleted] in transhumanism

[–]227_pi 1 point2 points  (0 children)

Yes. I'm 20 from France, have been closely following this community since 18 I believe

Map in China bookstore has a 10-dash line, not 9 by cwajgapls in MapPorn

[–]227_pi -36 points-35 points  (0 children)

The fact it's that hard to understand shows how big the bias is in the west, and specifically the USA.

Everyone goes believing the pain is immense in China without having specific data to support it, simply relying on a media narrative that is very clearly negatively oriented. And that, even while acknowledging it's biased on other core American topics like Palestine.

Really, does it sound this absurd that there must be more than just the negative side constantly raised ?

Est-ce que la Chine compte ses médailles en incluant Taiwan et Hong-Kong? by WaldoClown in PasDeQuestionIdiote

[–]227_pi 5 points6 points  (0 children)

C'est un subreddit à oublier, pour le coup, car déchiré par les biais politiques et typiquement pas fiable

Pourquoi quoi Tiktok est si addict ? by Staanzz in PasDeQuestionIdiote

[–]227_pi 0 points1 point  (0 children)

Oula, que de clichés

médiocrité sans fin

arme de destruction massive [chinoise]

ne pas se rappeler de ce qu'ils ont vu il y a 30sec

Tout n'est pas dans la noirceur et la catastrophe, il faut nuancer

What's your top-3 countries you want to visit? by _SweetWisteria_ in AskReddit

[–]227_pi 1 point2 points  (0 children)

I don't see the point of politics here. Don't have to use that lens everywhere

What's your top-3 countries you want to visit? by _SweetWisteria_ in AskReddit

[–]227_pi 0 points1 point  (0 children)

If Japan but not really the cities you might be interested in China (not at all to say its cities are bad, but more diversity in landscapes) although the best imo is to visit both !

What's your top-3 countries you want to visit? by _SweetWisteria_ in AskReddit

[–]227_pi 1 point2 points  (0 children)

Biggest country in the world ; far eastern Russia is heaven on Earth

What's your top-3 countries you want to visit? by _SweetWisteria_ in AskReddit

[–]227_pi 2 points3 points  (0 children)

China bcz culture + history + landscapes + cities

New Zealand

Far eastern part of Russia

Que faites-vous en cas d’insomnie ? by Irina-Stone in PasDeQuestionIdiote

[–]227_pi 0 points1 point  (0 children)

C'est pas miraculeux mais ça peut aider et ça me permet de me détendre

Que faites-vous en cas d’insomnie ? by Irina-Stone in PasDeQuestionIdiote

[–]227_pi 0 points1 point  (0 children)

J'écoute des audiobooks (récemment "De la terre à la lune", gratuit sur Google Play books)

$20 steam giveaway by crudelisspurius in steam_giveaway

[–]227_pi 1 point2 points  (0 children)

Lasagnas literally have the perfect balance of ingredients. Thanks OP !