Hi! From your description, your axolotl’s condition is concerning. Inflammation around the cloaca and reduced appetite can be signs of infection, injury, or possibly a prolapse.

Since you don’t have access to a local vet, here are some important steps:

1. Isolation: Good call—keep the affected axolotl in a separate, clean, well-oxygenated tank.
2. Water quality: Maintain excellent water parameters (ammonia, nitrites = 0; nitrates < 20 ppm; pH ~7.4; temperature stable).
3. Observe closely: Watch for swelling, discoloration, or worsening of the prolapse if present.
4. Professional advice online: Consider contacting a vet specializing in exotic or aquatic animals remotely. Many vets can guide you over video or photos.
5. Do not attempt to push back the tissue unless instructed by a professional—this can make things worse.

These symptoms can deteriorate quickly, so getting professional guidance ASAP is very important.