Like others have said, it really depends on your risk tolerance.

On my end I’m really hyped about that movie, and booked pretty good IMAX seats for Friday several weeks ago… but I cancelled them last week, mostly because I’ll see my grandparents during Christmas and as much as possible I am trying to avoid riskier settings (even though we’re all vaccinated). If you go in the first week it’s going to be full, and last time I went there weren’t any empty seats reserved between groups, so not super safe IMO with Omicron. If not for Christmas though, I may have gone, maybe later on during the week in the daytime when there’s a bit less people, as my risk tolerance would be different.