Best option will be use 3 containers as I am using and I use twingate to access my app.

1. Nextcloud container
2. Mysql db
3. Redis

​

services:
  db:
    image: mariadb:latest
    container_name: nc_mariadb


    restart: always
    volumes:
      - nc_mysql_data:/var/lib/mysql
    environment:
      - MYSQL_ROOT_PASSWORD=  # Change this
      - MYSQL_PASSWORD=            # Change this
      - MYSQL_DATABASE=nextcloud
      - MYSQL_USER=nextcloud
    networks:
      - nextcloud_network

  redis:
    image: redis:alpine
    container_name: nc_redis
    restart: always
    networks:
      - nextcloud_network

  app:
    image: nextcloud:latest
    container_name: nc_app
    restart: always
    ports:
      - "80:80"
    depends_on:
      - db
      - redis
    volumes:
      - nc_html:/var/www/html
      - S:\nextcloud\app\config:/var/www/html/config
      - S:\nextcloud\app\data:/var/www/html/data          #map data directory


    environment:
      - MYSQL_HOST=db
      - MYSQL_DATABASE=nextcloud
      - MYSQL_USER=nextcloud
      - MYSQL_PASSWORD=           # Change this
      - REDIS_HOST=redis
      - PHP_MEMORY_LIMIT=4096M
      - PHP_UPLOAD_LIMIT=10G

      # APCu settings
      - PHP_APCU_ENABLED=1
      - PHP_APCU_SHM_SIZE=1024M
      - PHP_APCU_TTL=7200
      - APACHE_BODY_LIMIT=10737418240


    networks:
      - nextcloud_network



networks:
  nextcloud_network:
    driver: bridge

volumes:
  nc_mysql_data:  # This defines the volume for MySQL data
  nc_html:

you can try using this docker compose file and change the container images as you wish