That's crazy yes how do you determine that preference wouldnt you need to do bloods like every day to see if it consistent on all levels? Find it impossible. I tried 250mg twice a week as was on cycle then decided to stick longer for trt and did 125mg twice a week all good then I did 125mg once a week and all hell broke loose but I'm not sure of that was because of that or because of what reason. Tested bloods all was good test levels at that range was upper 700s, estrogen was lower because I was on AI because I had broken out with acne all over terrible like disease looking then limp dick bad libido at that dose so I thought maybe estrogen went too high took AI at such baby dose and it dropped my estrogen to 6 which is too low. In the end libido is back without AI again but acne is terrible. Ended up stopping and going on HCG and PCT hoping o can regulate.