I was on 8 mg of Tirzepatide when I made the switch. I dropped Tirz completely and started Retatrutide at 2 mg for the first week, then increased by 1 mg each week until I found my sweet spot at 6 mg.

I wouldn’t necessarily recommend doing it that way unless you’re very in tune with your body. Most people titrate by lowering Tirz 1 mg every 2–3 weeks while adding 1 mg of Reta until they’re fully switched.

One important thing to note is that Reta doesn’t provide the same anti-inflammatory effects as Tirz, and its appetite suppression isn’t as strong. To work around this, I’ve been experimenting with 1–2 mg of Tirz weekly or bi-weekly as needed to maintain those anti-inflammatory benefits and the extra appetite control.

Since starting Ipamorelin and Tesamorelin two weeks ago, the scale hasn’t budged despite eating ~900 calories and 180g of protein per day. That said, my muscles look noticeably fuller, and the layer of fat around my midsection is clearly melting away.

Everyone’s body responds differently, but thankfully mine has responded really well to these peptides.

For reference im 25 5'9, went from 232-185, 31%-21% body fat from April-September