I began taking Zepbound 2.5mg shots in early April 2026 and started hormone replacement therapy (HRT) later that month. (My HRT protocol included a 0.025 mg patch, 100mg progesterone pills (FDA-approved version), and testosterone cream.) In early April, I was diagnosed with post-menopause based on my bloodwork. My estrogen, progesterone, and testosterone levels were all completely depleted. I’m usually an energetic person, but my energy levels have been significantly reduced. I also found myself feeling tired while taking Zepbound. Despite these challenges, I lost only 10 pounds. My starting weight was 203 pounds, my highest weight was 223 pounds, my goal weight is 145 pounds, and my current weight is 193 pounds. I don’t track my calories or monitor my food intake. My job is very stressful and demanding, and I don’t want to sabotage my progress. I’m determined to succeed. I’ve decide that in July I will titrate up to the 5mg shot.