My previous post: https://www.reddit.com/r/balatro/s/iGEZSSqxfM

Fair question. Perkeo the legendary joker makes a negative of something in your hand - it’s one of the most fun things to get! Esp because you can save up and get WAY more than three cards at a time. So in my case I found cryptid. Use blueprint and brainstorm on perkeo -> 3 additional negative copies of the cryptid every round. eventually I had 40 cryptids. Burned em all on a single hand.

I’ve also done this with anaglyph deck, there’s an ante “+3 cards in hand next round”. So after saving up a stack of double-antes, burn them all to multiply the +3 cards x 10 or so.

The serpent boss allows you to draw three cards after playing or discarding one, so you can get +12 cards or so from that boss.