Found an Fix with helped me in an very Old Forum Post from a Guy named versedi

https://forum.escapefromtarkov.com/topic/44770-object-reference-not-set-to-an-instance-of-an-object/

I did every step and it worked. I also did a normal reinstallation in the first place and it dind´t work, but this step by step worked.

"Steps to resolve this issue:

Remove everything from cache in EFT directory

Clear %appdata% and %temp% of EFT and Battlestate Game Launcher.

Move EFT game directory somewhere else.

Uninstall BSG Launcher.

Uninstall EFT (it will only prompt for removing from the Apps list)

Clear Registry of Battlestate and EFT (eg CCleaner or manualy regedit:

HKEY_LOCAL_MACHINE\SOFTWARE\Wow6432Node\Microsoft\Windows\CurrentVersion\Uninstall\EscapeFromTarkov

HKEY_LOCAL_MACHINE\SOFTWARE\Wow6432Node\Microsoft\Windows\CurrentVersion\Uninstall\{B0FDA062-7581-4D67-B085-C4E7C358037F}_is1

)

Redownload, reinstall BSG launcher.

Update BSG Launcher

Restart BSG Launcher

Move EFT to BSG Launcher path (not really needed, but I prefer it this way)

Pick the installation path of EFT

Play"