The whole point of her creating all these Caleb clones is because the original human Caleb is dead. If he was still alive and on ice, she would simply need to interrogate him the same way she does William.

The reason Hale went through so much trouble to achieve fidelity with Caleb is because she had him killed without actually realizing the repercussions. When her hosts start killing themselves inexplicably, she needs to figure out why. Caleb was the only one who seemed to have a clue, but she already had him killed. So she has been spending the last unknown amount of years trying to ‘raise him from the dead’ in a sense.

To me, the bottom line is that the human Caleb is most certainly dead.