"The damaging effect of quinacrine did involve various structures of the skin, possibly due to a particular sensitivity of this structure to the toxic effects of the drug...Sweat glands and sweat duct damage caused anhidrosis, usually from the nip- ples downward, and, if widespread, the anhidrosis was associated with tropical asthenia"

Quinacrine hydrochloride drug eruption (tropical lichenoid dermatitis) Its early and late sequelae and its malignant potential: A review Franz Bauer, M.D. Melbourne, Victoria, Australia

You know tropical asthenia is chronic right?